Hokkaido Research Seeds in Health and Medicine 2023

1-1 The pH-responsive cationic lipids with efficient endosomal release
1-2 Brain micro-inflammation at specific vessels under stress induce
      gastrointestinal failure
1-3 New Enzyme for Biosynthesis of Cyclic Peptides

Sapporo
Medical
University

2-1 Identification of a long non-coding RNA as a therapeutic target in gastric 
      cancer
2-2 Development of novel therapy and diagnosis by common factors in
      cardiovascular,  renal and metabolic diseases
2-3 Liver organoid model for pharmacokinetic assay
2-4 Development of CAR-T cells targeting cancer stem cell antigen for
      refractory osteosarcoma
2-5 Development of the innovative remedy and clinical application for
      Muscular Dystrophy
2-6 Screening of vivoEF inhibitors for site-specific therapy against bacterial
      infections

3-1 Therapeutic Agent for IBD "Long-Polyphosphate"
3-2 Anti-Cancer Agent "Ferrichrome"
3-3 Novel Agent for NASH "FGF9"
3-4 New Capillary Stem Cells “CapSCs”

4-1 Dataset for development of surgical operation supporting robot for small
      animals  - A canine spay surgery as an example -
4-2 Hypochlorous Acid-Responsive Thin Films that Exhibit Remarkable Color
      Changes
4-3 Hypochlorous Acid-Responsive Bilayer Hydrogels that Show Distinct
      Deformation
4-4 Bio- and Environment-Responsive Molecular Recognition Materials that
      Exhibit Remarkable Color Changes
4-5 Chemical defined medium for protein and nucleic acid production by
      Escherichia coli
      - Design CDM to express larger amount of recombinant Protein than
        natural Media -

National
Instirute of
Technology,
Hakodate
College